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Target intelligence / Profile preview
Glycerophosphodiester phosphodiesterase domain-containing protein 1 (GDPD1)
- Target
- GDPD1
- Molecular classification
- Enzyme
01
Overview
Glycerophosphodiester phosphodiesterase domain-containing protein 1 (GDPD1) is a member of the glycerophosphodiester phosphodiesterase family of enzymes. It hydrolyzes deacylated glycerophospholipids, specifically lysoglycerophospholipids, to yield lysophosphatidic acid (LPA) and corresponding amines, playing a role in glycerol metabolism and lipid remodeling[2][5][1]. If additional structured data is needed—such as approved drugs, biomarkers, or clear disease roles—there is currently no strong evidence of these from the provided sources, indicating this protein is mainly recognized for its biochemical activity as an enzyme and not yet a major therapeutic target.
- Other names
- Lysophospholipase D GDPD1GDE4FLJ37451Glycerophosphodiester phosphodiesterase 4GDPD1
02
Biological functions
Hydrolysis of lysoglycerophospholipidsGlycerol metabolismProduction of lysophosphatidic acid (LPA)
03
Disease associations
Other (specific disease associations not well established in current sources)
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