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Glycoprotein M6B pseudogene 3 (GPM6BP3) is classified as a human pseudogene related to the functional gene GPM6B, which encodes the protein neuronal membrane glycoprotein M6-b. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional due to mutations, truncations, or lack of regulatory elements[7]. GPM6BP3 does not produce a functional protein and is not considered a druggable target, receptor, enzyme, transporter, or biomarker. The functional counterpart, glycoprotein M6B (GPM6B), plays roles in neural development, cell communication, and has been reported to act as a tumor suppressor, but these roles are not attributable to the pseudogene GPM6BP3[1][4][7]. Additional Notes: - Pseudogenes, like GPM6BP3, are often annotated in genetic data but lack protein-coding or regulatory function, so they are generally excluded from therapeutic target databases. - If you intended to query the functional GPM6B gene or protein, use "neuronal membrane glycoprotein M6-b" (GPM6B) instead, which is a membrane protein with biological activity and disease relevance[1][4]. - No evidence currently exists for GPM6BP3 involvement in drug interaction, disease, or biomarker development[7].
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