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GLYCTK antisense RNA 1 (GLYCTK-AS1)
- Target
- GLYCTK-AS1
- Molecular classification
- Long non-coding RNA (lncRNA)
01
Overview
GLYCTK antisense RNA 1 (GLYCTK-AS1) is a long non-coding RNA (lncRNA) gene transcribed from the antisense strand in proximity to the GLYCTK gene on chromosome 3[3][5]. As an lncRNA, it does not encode a protein but may have regulatory roles in gene expression, particularly through participation in ceRNA (competing endogenous RNA) networks that modulate mRNA and miRNA activity[2]. Recent studies implicate GLYCTK-AS1 in cancer biology, where its expression and interactions may impact prognosis and immune cell infiltration in glioma. However, its precise biological function and mechanisms remain under investigation, and it is not currently considered a direct therapeutic target or a receptor/enzyme/transporter[2][5].
- Other names
- GC00U933051GC03M052324GC03M052288GC03M054646
02
Biological functions
May act as a regulatory RNA in competitive endogenous RNA (ceRNA) networks, influencing gene expression by binding miRNAs[2]Likely functions in regulation of gene expression at the RNA level[2]
03
Disease associations
Potential involvement in cancer, specifically low-grade glioma (LGG), as part of lncRNA-mediated regulatory networks[2]
04
Biomarkers
Potential prognostic biomarker in low-grade glioma, based on differential expression studies[2]
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