GM2A pseudogene 2 (GM2AP2)

GM2A pseudogene 2 (GM2AP2) is a non-functional gene sequence on the human genome, designated as a pseudogene of the GM2A locus. Unlike the functional GM2A gene, which encodes the ganglioside GM2 activator protein involved in lysosomal degradation of GM2 ganglioside, the GM2A pseudogene 2 has no known protein product or biological function and is not considered a therapeutic or pharmacological target. It is catalogued in genome databases (e.g., NCBI Gene 100287900, Ensembl ENSG00000239428) on chromosome 1 and exists as a remnant of gene duplication, with no known clinical, diagnostic, or therapeutic relevance[7]. Key points: - This is a pseudogene, meaning it is a non-coding, non-functional genetic element. - There is no evidence GM2AP2 produces a protein or acts as a drug target. - It should not be confused with the functional GM2A gene/protein, which has significant biological and disease relevance[1][3][5][7]. - "GM2A pseudogene 2" is not a receptor, enzyme, transporter, or other canonical therapeutic or biological target. If you need information on the functional gene/protein (GM2A, ganglioside GM2 activator), let me know.

Other names

GM2 ganglioside activator pseudogene 2GM2AP2