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Golgin subfamily A member 6-like protein 1 (GOLGA6L1)
- Target
- GOLGA6L1
- Molecular classification
- Other (Golgin family; Golgi matrix protein)
01
Overview
Golgin subfamily A member 6-like protein 1 (GOLGA6L1) is a member of the golgin family of Golgi matrix proteins that are involved in maintaining Golgi structure and possibly tethering vesicles at the Golgi apparatus. While the overall function of GOLGA6L1 specifically is not well-characterized, golgins generally play roles in Golgi ribbon formation, vesicle capture, and organellar integrity. There is currently no evidence that GOLGA6L1 acts as a classical therapeutic target such as a receptor, enzyme, or transporter. Gene variations in GOLGA6L1 have been linked to Autism Spectrum Disorder, but its precise biological role and involvement in disease mechanisms remain unclear[2][3][4].
- Other names
- Golgin A6 family like 1Golgi autoantigenGOLGA6L1golgin subfamily a, 6-like 1GG6L1_HUMAN
02
Biological functions
Golgi structure maintenanceprotein traffickingvesicle tetheringpossibly protein sorting
03
Disease associations
Other (associated with Autism Spectrum Disorder[4])
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