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Target intelligence / Profile preview
Golgin subfamily A member 8T (GOLGA8T)
- Target
- GOLGA8T
- Molecular classification
- Other, golgin family, Golgi apparatus structural protein
01
Overview
Golgin subfamily A member 8T (GOLGA8T) is a protein encoded by the GOLGA8T gene in humans and belongs to the golgin protein family, which are characterized by their localization to the Golgi apparatus and involvement in maintaining its structure and organization. GOLGA8T is a predicted protein coding gene associated primarily with the organization of the Golgi apparatus, specifically being present in the Golgi cis cisterna, cisterna membrane, and the cis-Golgi network. No direct evidence supports its role as a therapeutic target, drug interactions, or pharmacological mechanism of action. The gene is associated with rare genetic disorders linked to structural chromosomal changes, such as Chromosome 15q13.3 deletion syndrome and Adams-Oliver syndrome. No safety concerns or established use as a biomarker are described in current knowledge.
- Other names
- Golgin A8 family member TGOLGA8Tgolgin subfamily A member 8T
02
Biological functions
Golgi organizationMaintenance of Golgi structurePredicted involvement in Golgi cisterna and network
03
Disease associations
Chromosome 15q13.3 deletion syndromeAdams-Oliver syndrome
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