Target intelligence / Profile preview

GPA33 antisense RNA 1 (GPA33-AS1)

Target: GPA33-AS1
Molecular classification: Long non-coding RNA, Other (non-coding RNA)

Overview

GPA33 antisense RNA 1 (GPA33-AS1) is a long non-coding RNA transcript located in the genomic region antisense to the GPA33 gene, which encodes Glycoprotein A33, a cell surface marker expressed in intestinal epithelial cells[1][2]. Unlike GPA33, GPA33-AS1 does not code for a protein. Its function, disease association, and therapeutic relevance are currently unknown or unreported in the published literature. Key distinction: - GPA33-AS1 is *not* a protein-coding gene, receptor, enzyme, or established therapeutic target. - The well-characterized therapeutic target is GPA33 (Glycoprotein A33), not GPA33-AS1. GPA33 is targeted in antibody-based therapies for colorectal cancer due to its surface expression in intestinal tissues and neoplasms[1][2]. Currently, there is no evidence that GPA33-AS1 serves as a therapeutic target, biomarker, or a participant in disease mechanisms.

Other names: GPA33-AS1lncRNA-GPA33-AS1

Biological functions

Other (no confirmed or widely recognized function currently reported for this lncRNA)

Disease associations

Other (no established links to diseases as of current literature)

Beyond the preview

Go deeper on GPA33 antisense RNA 1 (GPA33-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on GPA33 antisense RNA 1 (GPA33-AS1).

Explore the full profile