Target intelligence / Profile preview

GPR55 cis regulatory suppressor of immune response RNA (GCSIR)

Target
GCSIR
Molecular classification
Long non-coding RNA (lncRNA), Other
01

Overview

GPR55 cis regulatory suppressor of immune response RNA (GCSIR) is a human long non-coding RNA gene (lncRNA) located at cytogenetic region 2q37. It is also named Lnc-ITM2C-1. GCSIR is annotated as a non-protein-coding transcript, and available data do not identify it as a direct therapeutic target such as a receptor, enzyme, or transporter. Its function is inferred to be cis-acting regulatory control of immune response, possibly through modulation of GPR55 or immune-related pathways, but details are limited. No information is currently available about its involvement in major disease categories, as a biomarker, or as the target of specific drugs. Its role may be relevant in the context of viral infection, based on isolated findings linking similar lncRNAs to viral replication influence, but this is not confirmed for GCSIR specifically[1][2][3][4][5][6][8][9].

Other names
Lnc-ITM2C-1LNC-ITM2C-1
02

Biological functions

Immune response regulation (putative)Other
03

Disease associations

Other (possibly involved in viral infection, e.g., hepatitis C)

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