GRAM domain containing 4 pseudogene 2 (GRAMD4P2)

GRAM domain containing 4 pseudogene 2 (GRAMD4P2) is a non-coding processed pseudogene locus in the human genome, located at chromosome 17p13.1. Pseudogenes like GRAMD4P2 arise either by retrotransposition (processed pseudogenes), or duplication and subsequent loss of function. GRAMD4P2 is annotated as a processed pseudogene per HGNC and NCBI standards, meaning it is a genomic sequence derived from a functional parent gene but mutated such that it cannot produce a functional protein. Pseudogenes occasionally play roles in regulating their parent genes via RNA mechanisms—such as serving as miRNA decoys or through siRNA-mediated processes—but there is no described functional activity, disease association, or regulatory significance specifically attributed to GRAMD4P2 in the current literature. Therefore, it is not considered a therapeutic target, biomarker, or associated with safety concerns.

Other names

GRAMD4P2RWD domain containing 4 pseudogene 2