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The Gram-positive bacterial cell membrane is a phospholipid bilayer that lies beneath a thick peptidoglycan cell wall. It's responsible for maintaining cellular integrity, controlling the passage of molecules in and out of the cell, and facilitating various metabolic processes. It is the primary target for cationic antimicrobial agents like cetylpyridinium chloride (CPC), which disrupt the membrane structure, leading to cell death.
Disruption of phospholipid bilayer integrity, leading to leakage of intracellular contents, metabolic inhibition, and cell death.
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