Target intelligence / Profile preview

Grass Pollen Allergen Epitopes (N/A)

Target
N/A
Molecular classification
Protein epitopes, Allergens
01

Overview

Grass pollen allergen epitopes are specific regions on grass pollen proteins recognized by the immune system, triggering IgE-mediated allergic responses. Major allergen groups include group 1 (e.g., Phl p 1), groups 2/3 (e.g., Phl p 2/Phl p 3), and group 5 (e.g., Phl p 5). These epitopes can be linear or conformational, with cross-reactivity occurring due to sequence homology among different grass species. Repeated exposure leads to increased IgE production and clinical sensitivity. Molecular weights range from ~6-60 kDa. The presence of multiple IgE binding sites per molecule contributes to their high allergenic potential.

Other names
Phl p 1 epitopesPhl p 2 epitopesPhl p 3 epitopesPhl p 5 epitopesGroup 1 grass pollen allergensGroup 2 grass pollen allergensGroup 3 grass pollen allergensGroup 5 grass pollen allergens
02

Mechanism of action

N/A

03

Biological functions

IgE bindingB cell activationImmune response inductionAllergic sensitization
04

Disease associations

Allergic rhinitisAsthmaAllergic conjunctivitisGrass pollen allergy
05

Safety considerations

AnaphylaxisSevere allergic reactions
06

Biomarkers

Allergen-specific IgE levelsSkin prick test reactivity

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