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Target intelligence / Profile preview
Green Tea Extract (GTE)
- Target
- GTE
- Molecular classification
- Polyphenol mixture, Antioxidant mixture, Dietary supplement
01
Overview
Green tea extract is a concentrated form of bioactive compounds from green tea (Camellia sinensis), primarily polyphenols such as catechins and epigallocatechin gallate (EGCG). It exhibits antioxidant, anti-inflammatory, and potentially anti-cancer properties. While generally safe, high doses can cause adverse effects.
- Other names
- Camellia sinensis extractGreen tea polyphenolsEGCG (Epigallocatechin gallate)Catechins
02
Mechanism of action
Antioxidant activity via free radical scavenging and metal ion chelation; modulation of cell signaling pathways via interaction with cell surface receptors and intracellular transcription factors.
03
Biological functions
Antioxidant activityModulation of lipid metabolismModulation of glucose homeostasisAnti-inflammatory activity
04
Disease associations
Cardiovascular diseaseObesityNeurodegenerative diseasesCancer (potential)
05
Safety considerations
Gastrointestinal upset (high doses)Liver toxicity (rare, high doses)Potential drug interactionsBioavailability affected by food components
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