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Target intelligence / Profile preview
Group A carbohydrate polyrhamnose backbone (GAC polyrhamnose backbone)
- Target
- GAC polyrhamnose backbone
- Molecular classification
- Polysaccharide, Cell wall glycopolymer, Other
01
Overview
The Group A carbohydrate polyrhamnose backbone is a highly conserved polysaccharide chain within the bacterial cell wall of Group A Streptococcus and related ovoid Gram-positive species, formed of alpha-linked L-rhamnose residues and acting as a key scaffold for side-chain antigenic variations, thus supporting cell wall structure, virulence, and immune evasion.
- Other names
- Group A carbohydrate backboneLancefield Group A antigen backbonepolyrhamnose backbonerhamnanRha-CWPS
02
Biological functions
Cell wall architecture and biogenesisImmune evasionStructural integrityHost-pathogen interaction
03
Disease associations
InfectionInflammation
04
Biomarkers
Group A carbohydrate antigen detectionGAC-based diagnostics
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