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Target intelligence / Profile preview
Group B Streptococcus capsular polysaccharide serotype III (GBS CPS type III)
- Target
- GBS CPS type III
- Molecular classification
- Polysaccharide antigen
01
Overview
The Group B Streptococcus capsular polysaccharide serotype III is a sialylated repeating unit polysaccharide composed of glucose, galactose, N-acetylglucosamine, and sialic acid, featuring a disaccharide backbone with a branched trisaccharide side chain linked β-(1→4) to the backbone and terminating in α-(2→3)-linked sialic acid; it serves as a key surface antigen and virulence factor enabling immune evasion through antiphagocytic activity, with structural similarity to other GBS serotypes but distinct glycosidic linkages (e.g., β-D-GlcNAc-(1→6) between repeating units).
- Other names
- GBS type III capsular polysaccharideType III CPS
02
Biological functions
Antiphagocytic factorVirulence factor
03
Disease associations
Infection
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