Group B Streptococcus Surface Protein Antigens (GBS Surface Proteins)

Group B Streptococcus (GBS) surface protein antigens are a collection of proteins expressed on the bacterial cell surface that contribute to virulence, immune evasion, and host-pathogen interactions. Key examples include β Protein (involved in complement evasion), BspC (promoting brain endothelium adhesion), BPS Protein (eliciting protective immunity), Alpha C Protein Family (mediating adhesion/invasion), and C5a Peptidase (disrupting neutrophil recruitment). These proteins are potential targets for vaccine development and diagnostic assays, and are involved in various functions such as adherence to host cells, invasion into epithelial barriers, binding host immune regulators, and inducing inflammatory responses.

Other names

Streptococcus agalactiae Surface ProteinsGBS Surface Antigensβ ProteinBspCBPS ProteinAlpha C Protein FamilyC5a Peptidase