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Growth Hormone-Releasing Hormone Inhibitor

Molecular classification: Other

Overview

A growth hormone-releasing hormone (GHRH) inhibitor is a molecule that suppresses the action or release of GHRH, a hypothalamic peptide responsible for stimulating the secretion of growth hormone (GH) from the anterior pituitary gland. By inhibiting GHRH, these agents ultimately reduce GH production and its downstream effects.

Other names: GHRH InhibitorGrowth Hormone-Releasing Hormone Antagonist

Mechanism of action

Blocks synthesis/release/action/binding/signaling related to endogenous/exogenous GHRH

Biological functions

Negative regulation of growth hormone secretionRegulation of IGF-1 productionRegulation of somatotroph activity

Disease associations

AcromegalyCancer (certain types)

Interacting drugs

Somatostatin

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