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Growth hormone secretion from anterior pituitary gland
01
Overview
Growth hormone secretion from the anterior pituitary gland refers to the physiological process whereby somatotroph cells in the anterior pituitary release growth hormone (GH) into the bloodstream. This secretion is regulated by hypothalamic growth hormone-releasing hormone (GHRH) and inhibited by somatostatin, as well as regulated by metabolic and feedback signals, such as insulin-like growth factor 1 (IGF-1). It is a key process for normal growth, metabolism, and cellular regeneration but is not itself a molecular target for drug development.
- Other names
- Secretion of growth hormone by anterior pituitaryGH secretionPituitary GH secretionSomatotroph secretion
02
Biological functions
Growth hormone secretionEndocrine regulationGrowth regulationMetabolism regulation
03
Disease associations
Growth disordersAcromegalyDwarfismPituitary adenomaOther
04
Biomarkers
GH levelsIGF-1 levels
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