Guanine nucleotide in DNA (G (only in the context of nucleic acid notation, not as a target abbreviation))

Guanine nucleotides in DNA refer to the **deoxyribonucleotide units containing the base guanine**, a purine nitrogenous base (C\(_5\)H\(_5\)N\(_5\)O), which pair specifically with cytosine via three hydrogen bonds, stabilizing the DNA double helix[1][2][3][4][5][7]. The arrangement and sequence of guanine bases within DNA encode genetic information and play a crucial role in defining the genetic code and gene expression[3][7]. Alterations or lesions involving guanine can contribute to mutations and disease, but "guanine nucleotides in DNA" as a phrase does not define a discrete, actionable molecular target[2][3][6]. Key points: - **Guanine** is a fundamental DNA building block but not a "target" in the biological sense of drug or therapeutic intervention[1][3][4][6]. - If a specific guanine-modifying enzyme, nucleotide transporter, or guanine-related protein is intended, a more precise name is required. **This entry is not a recognized molecular target or receptor.**

Other names

Guanine base in DNADeoxyguanosine monophosphate (dGMP, when referring to the nucleotide)Guanine (when referring to the base)