H3 histone pseudogene 1 (H3P1)

H3 histone pseudogene 1 (H3P1) is a non-coding DNA sequence annotated as a pseudogene due to its high sequence similarity to the histone H3 gene family but lacking evidence of protein-coding function or canonical roles in chromatin biology[4]. Pseudogenes like H3P1 often arise from gene duplication or retrotransposition and typically do not encode functional proteins[4]. Unlike functional histone H3 variants such as H3.1 or H3.3, H3P1 does not form part of nucleosomes, contribute to chromatin structure, undergo histone modifications, or participate in processes like transcriptional regulation, DNA repair, or cell cycle control[1][2][3]. No role in disease, interaction with drugs, or biomarker utility has been described. If your intent was to refer to functional histone H3 molecules or their variants (e.g., H3.1, H3.3), those are real molecular targets involved in chromatin regulation and epigenetics, but H3P1 itself is not a target nor is it an established functional gene[1][3].

Other names

H3 histone pseudogene 1H3P1p02