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H3 histone pseudogene 13 is a non-protein coding pseudogene in the human genome. It does not encode a functional histone protein, enzyme, receptor, or other druggable target and should not be confused with active histone H3 variants such as H3.1, H3.2, and H3.3, which are highly conserved core nucleosomal proteins involved in the regulation of chromatin structure and gene expression[1][3]. There is no evidence in the scientific literature that H3P13, or the alias p19 as used here, has any established biological role, disease association, or relevance as a therapeutic target. If querying for histone H3 proteins or their cancer-associated mutants (e.g., H3F3A K27M mutation), refer instead to their protein-coding gene symbols (such as H3F3A or H3F3B)[1][3]. No drugs, mechanisms, biomarkers, or safety concerns are associated with H3 histone pseudogene 13. If more information is required on functional H3 histone variants or chaperones involved in chromatin biology, see references to canonical H3 or H3.3 proteins[1][3]. If instead your interest is in a different entity commonly abbreviated as “p19,” provide additional context for accurate identification.
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