Target intelligence / Profile preview

H3 histone pseudogene 28 (H3P28)

Target
H3P28
Molecular classification
Other (pseudogene), Not a receptor, enzyme, transporter, ion channel, or established histone variant
01

Overview

H3 histone pseudogene 28 (H3P28), also referred to by the alias "p40", is an annotated pseudogene in the human genome. Unlike canonical histone genes (such as H3.1, H3.2, H3.3), pseudogenes do not code for functional proteins and are typically remnants of evolutionary events. H3P28 has no established biological function, disease relevance, or recognized role in drug development. The use of the alias "p40" for this gene is potentially confusing as "p40" is more commonly associated with unrelated proteins in oncology and immunology. In summary, H3 histone pseudogene 28 is not a receptor, enzyme, nor a therapeutic target, and there is no evidence of functional or clinical significance attached to this entity.

Other names
H3P28p40
02

Mechanism of action

Not applicable. No known mechanisms as it is not a drug target.

03

Biological functions

None established. As a pseudogene, H3P28 is not known to encode a functional protein or carry out cellular functions.
04

Disease associations

None established. There is no evidence in literature or genetic databases associating H3 histone pseudogene 28 with human disease or pathology.
05

Safety considerations

None. There are no relevant safety concerns or challenges mentioned for this pseudogene.
06

Interacting drugs

None. Pseudogenes are not targeted by drugs, and there are no reported interactions.
07

Biomarkers

None. It is not used as a biomarker for patient selection or efficacy monitoring.

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