Target intelligence / Profile preview

H3 histone pseudogene 44 (H3P44)

Target: H3P44
Molecular classification: Histone pseudogene, Other

Overview

H3 histone pseudogene 44 (H3P44) is a presumed, noncoding genomic sequence annotated as a pseudogene in histone family H3. Pseudogenes such as H3P44 do not encode a functional histone protein, and no evidence supports their translation or direct impact on cellular processes. Canonical histone H3 variants, including H3.1, H3.2, H3.3, H3.Y, and H3T, regulate chromatin accessibility, gene expression, and cellular differentiation through incorporation into nucleosomes and various post-translational modifications[1][6][4][5][2]. There is no evidence to support a role for H3P44 as a therapeutic target, receptor, enzyme, or biomarker. The aliases "H3P44," "p55," and "H3.8" are not widely recognized in the context of human histone nomenclature and may represent annotation errors[5][2].

Other names: H3P44p55H3.8

Mechanism of action

None.

Biological functions

None established.

Disease associations

None established for H3P44

Safety considerations

None.

Interacting drugs

None.

Biomarkers

None.

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