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Haemophilus influenzae type b capsular polysaccharide-conjugated outer membrane protein complex of Neisseria meningitidis
- Molecular classification
- Polysaccharide-protein conjugate, Vaccine Antigen
01
Overview
This is a conjugate vaccine antigen composed of the capsular polysaccharide from *Haemophilus influenzae* type b (Hib) covalently linked to an outer membrane protein complex derived from *Neisseria meningitidis*. The conjugation enhances immunogenicity, especially in infants and young children, by converting the polysaccharide into a T-cell dependent antigen. It is used in vaccines for prevention of invasive diseases caused by *Haemophilus influenzae* type b.
- Other names
- Haemophilus influenzae Type B Capsular Polysaccharide Meningococcal Outer Membrane Protein Conjugate AntigenHib-MenOMPCLUY6P8763WHaemophilus Influenzae Type B Conjugate Hib
02
Mechanism of action
Induction of T-cell dependent antibody response against Hib polysaccharide
03
Biological functions
Antigen presentationInduction of humoral immune responseActive immunization
04
Disease associations
InfectionPrevention of Haemophilus influenzae type b disease
05
Interacting drugs
PedvaxHIB
2 more in the full profile.
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