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"Hair growth promotion" is not the name of a specific molecule or receptor. Instead, it describes a physiological process involving multiple molecular pathways and cell types that regulate the development, cycling, and regeneration of hair follicles. Key signaling pathways involved include WNT/β-catenin, BMP/TGF-beta family members, FGF family members such as FGF7, ERK activation for cell proliferation, Bcl-2 for apoptosis suppression, and others. Drugs like minoxidil act by prolonging the anagen (growth) phase and stimulating dormant follicles to enter active growth. Platelet-derived factors can also stimulate cellular proliferation within hair follicles through various mechanisms including ERK activation and β-catenin signaling[1][2][4]. "Hair growth promotion" is therefore not itself a therapeutic target but rather an outcome achieved by modulating several distinct molecular targets.
Prolongation of the anagen phase of the hair cycle; Induction of resting follicles into active growth; Cellular proliferation and anti-apoptotic signaling in follicular cells
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