Target intelligence / Profile preview

HDL Cholesterol Metabolism

Molecular classification: Metabolic Pathway

Overview

HDL cholesterol metabolism refers to the complex biological processes governing the synthesis, maturation, remodeling, and catabolism of HDL particles. HDL is a class of lipoproteins primarily responsible for reverse cholesterol transport (RCT), a process by which excess cholesterol is removed from peripheral tissues and delivered to the liver for excretion or recycling.

Biological functions

Reverse cholesterol transportCholesterol effluxLipid metabolismSteroid hormone productionImmune modulation

Disease associations

Cardiovascular diseaseAtherosclerosisDyslipidemia

Biomarkers

HDL-C levelsApoA-I levels

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