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Heart function in Traditional Chinese Medicine (TCM) represents a holistic functional system rather than a specific molecular target or anatomical organ. Known as the 'Monarch' of the Zang-Fu organs, the TCM Heart is responsible for governing the blood and vessels to ensure systemic circulation and housing the 'Shen' (spirit), which encompasses consciousness, memory, and emotional regulation [1][3]. Pathological states such as Heart Qi deficiency or Heart Fire blazing manifest as a combination of cardiovascular symptoms (palpitations, chest pain) and neuropsychiatric issues (insomnia, delirium, anxiety) [2][4]. Because this concept describes a broad physiological framework involving multiple biological pathways, it is not considered a therapeutic target in the modern pharmacological sense, such as a receptor or enzyme [5]. Instead, it serves as a diagnostic category for multi-component therapies, such as herbal formulas and acupuncture, which aim to modulate the body's systemic balance [3][5].
Traditional Chinese Medicine interventions aim to restore homeostatic balance (Yin-Yang) and the flow of vital energy (Qi) and Blood within the Heart system through tonification of deficiency, clearing of Heat/Fire, or resolving Blood stasis [1][2].
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