Heat-responsive protein 12 pseudogene (HRSP12 pseudogene)

The **Heat-responsive protein 12 pseudogene (HRSP12 pseudogene, ENSG00000270542)** is a nonfunctional DNA segment that resembles the functional heat-responsive protein 12 gene. Pseudogenes are characterized by similarities to known genes but contain disablements—such as premature stop codons or frameshifts—that prevent them from encoding a functional protein[6]. HRSP12 itself, in its functional form, is heat-responsive and tissue-specific, related structurally to heat shock proteins (Hsp70/Hsp90) and involved in responses to thermal stress in certain species such as mouse and rat[1]. The pseudogene variant represented by ENSG00000270542 in humans is catalogued in genome databases but does not produce a functional protein. Generally, HRSP12 pseudogene has no known direct biological function, disease role, interacting drugs, or clinical biomarker relevance in humans[6][2][3]. For the purposes of drug discovery or molecular targeting, **ENSG00000270542 — Heat-responsive protein 12 pseudogene — should not be considered a valid therapeutic target**. If you require information on the functional HRSP12 protein, that would be a different query; this entry is specifically a pseudogene.

Other names

Heat-responsive protein 12HRSP12ENSG00000270542

None (no known mechanism of action; pseudogenes are not targeted by drugs)