Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) pseudogene

This entry is a *pseudogene* related to the HSPA5 (heat shock 70kDa protein 5, also known as BiP or GRP78, glucose-regulated protein 78kDa) gene. Pseudogenes are gene-like sequences that generally do not encode functional proteins and typically have no direct biological activity or role as a therapeutic target. No known roles in disease, drug interactions, or biomarker utility have been described for this pseudogene variant[1][5].\n\nKey clarification: This entry should not be confused with the protein-coding gene **HSPA5**, which is biologically significant and serves as a molecular chaperone involved in protein quality control, ER stress, and is a target of therapeutic interest in cancer and infectious disease[2][3][4]. The pseudogene encoded by ENSG00000250746 does **not** have the same functions and is not a drug target. If detailed information about the protein-coding HSPA5 gene is needed, a different entry should be used.

Other names

LOC100288073ENSG00000250746heat shock 70kDa protein 5 pseudogeneheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) pseudogeneAC105250.1