Heat shock protein 90 alpha family class A member 2 pseudogene (HSP90AA2P)

HSP90AA2P is a predicted heat shock protein 90 alpha family class A member 2 pseudogene. It shares sequence similarity with functional HSP90 proteins, which are highly conserved molecular chaperones involved in the folding, maturation, and degradation of cellular proteins. HSP90AA2P itself lacks protein-coding function and is not established as a direct participant in protein folding, signaling, or disease mechanisms. The functional variants of HSP90 are well-studied for their critical roles in cellular stress responses and have clinical significance in cancer therapy as therapeutic targets, but HSP90AA2P is not among the protein-coding, druggable HSP90 family members. If your interest is in pharmacological targets within the HSP90 family, you should look at protein-coding genes such as "Heat shock protein 90 alpha" (HSP90AA1) or "Heat shock protein 90 beta" (HSP90AB1).

Other names

HSP90AA2PHSP90AA2Heat shock protein HSP 90-alpha A2 pseudogeneHSP90ALPHAHeat shock 90 kDa protein 1 alpha-like 3HSPC2HSPCAHeat shock protein family C member 2

null for the pseudogene. For functional HSP90 proteins, mechanism of action typically involves inhibition of ATP binding to disrupt chaperone activity.