heat shock protein family D (Hsp60) member 1 pseudogene 18 (HSPD1P18)

**HSPD1P18** (heat shock protein family D (Hsp60) member 1 pseudogene 18) is a human pseudogene located on chromosome 5[7]. Pseudogenes are generally non-functional copies or fragments of known genes that have lost their ability to encode functional proteins due to mutations or deletions[8]. HSPD1P18 is related by sequence similarity to HSPD1, which encodes heat shock protein 60 (Hsp60, a mitochondrial chaperonin), but HSPD1P18 itself does not produce a functional protein[3][1][5]. There is currently no evidence linking HSPD1P18 to disease or therapeutic targeting, nor is it documented to serve as a regulatory RNA or a biomarker. Like other pseudogenes, it may be transcribed, but any such function (for example, as a competitive endogenous RNA) is speculative and not substantiated for HSPD1P18 in the literature[2][8]. Key Points: - HSPD1P18 is **not a therapeutic target** (not a receptor, enzyme, transporter, etc.), but a noncoding pseudogene[1][3]. - No known alternative names except the synonym HSPD1-1P[3]. - No reported involvement in disease, biomarker utility, or drug interaction. - The naming and annotation of this entity are correct as per major gene databases[1][3][5][7]. - As a pseudogene, its biological and clinical relevance is minimal or unknown; pseudogenes rarely have direct biochemical or therapeutic relevance unless proven otherwise.

Other names

HSPD1-1P