Target intelligence / Profile preview

Heat shock protein family D member 1 pseudogene 19 (HSPD1P19)

Target
HSPD1P19
Molecular classification
Pseudogene, Other
01

Overview

HSPD1P19, also known as "heat shock protein family D (Hsp60) member 1 pseudogene 19," is a pseudogene in the human genome[1][4]. Pseudogenes are DNA sequences that closely resemble known protein-coding genes but have accumulated mutations that prevent protein expression, often making them nonfunctional[8]. HSPD1P19 is related by sequence homology to HSPD1, a gene encoding the mitochondrial chaperonin Hsp60, but HSPD1P19 itself is non-coding and lacks biological or therapeutic relevance as a drug target. There are no drugs, validated biomarkers, therapeutic mechanisms, or disease linkage ascribed to HSPD1P19. Some pseudogenes may have regulatory roles at the RNA level, such as generation of non-coding RNAs or miRNA decoys, but there is no specific evidence of such function for HSPD1P19[2].\n\nKey clarification:\n- HSPD1P19 is a **pseudogene** and is not considered a valid drug target, receptor, enzyme, transporter, or functional protein.\n- Any functional or disease relevance ascribed to the parent gene (HSPD1/Hsp60) does not extend to HSPD1P19[4][5][7].\n- If your intent is to refer to the protein-coding chaperonin, the correct target is **Heat shock protein family D member 1 (HSPD1, Hsp60)**[5][7].\n\nSpecies specificity:\n- The queried gene is annotated in humans and denoted by NCBI Gene ID 100463288[1][4].

Other names
HSPD1-18Pheat shock protein family D (Hsp60) member 1 pseudogene 19
02

Biological functions

Other (pseudogenes are generally considered nonfunctional, but may sometimes play a role in post-transcriptional regulation, such as acting as miRNA decoys or sources of regulatory RNAs in rare cases)
03

Disease associations

Other (no direct disease association reported)

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