Target intelligence / Profile preview

Heat shock protein family E (Hsp10) member 1 pseudogene 18 (HSPE1P18)

Target
HSPE1P18
Molecular classification
Other (Pseudogene)
01

Overview

Heat shock protein family E (Hsp10) member 1 pseudogene 18 (HSPE1P18) is a pseudogene—a non-functional genomic DNA sequence similar to a functional gene but generally unable to encode a functional protein product, due to mutations or sequence alterations[6][7][8]. It is related by sequence homology to the functional HSPE1 gene, which encodes the mitochondrial co-chaperonin Hsp10 involved in protein folding, but HSPE1P18 itself does not produce a functional protein[6][7][8]. While some pseudogenes are transcribed and can participate in gene regulatory networks through non-coding RNA effects, there is no specific evidence that HSPE1P18 has such a role, nor is there any association with disease or therapeutic intervention[2][8]. In summary, HSPE1P18 is a pseudogene of Hsp10, not a functional protein or drug target; it is not associated with known drug interactions, disease states, or biomarker status[6][7][8].

Other names
HSPE1 pseudogene 18
02

Mechanism of action

None

03

Biological functions

No direct biological function as a proteinCompeting for regulatory elements as non-coding RNA (possible)Acting as potential regulators of gene expression through RNA-mediated mechanisms in rare instances, but such activity is not established for HSPE1P18 specifically
04

Disease associations

None established for this specific pseudogene; in general, some pseudogenes are implicated as regulatory RNAs or decoys in cancer or other diseases, but there is no evidence for HSPE1P18

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