Heat shock protein family E member 1 pseudogene 8 (HSPE1P8)

Heat shock protein family E member 1 pseudogene 8 (HSPE1P8) is annotated as a human pseudogene, meaning it is a DNA sequence resembling a functional gene but is generally nonfunctional due to accumulated mutations and lack of transcription or translation into a protein. There are no reports indicating that HSPE1P8 is expressed as a protein or has any direct biological activity in human cells. Pseudogenes such as HSPE1P8 are occasionally transcribed into non-coding RNAs, but there is no evidence for any such function, biological effect, disease association, or druggability for HSPE1P8 in the scientific literature or major biological databases[4]. This distinguishes it from related functional family members (e.g., HSPE1, which encodes mitochondrial Hsp10), but HSPE1P8 itself is not considered a molecular target in drug discovery or therapeutic research. If you require information about a functional protein target in the heat shock protein E (HSPE) family, refer to the canonical gene HSPE1 ("Heat shock protein family E member 1") which encodes the mitochondrial co-chaperonin Hsp10. HSPE1P8, by contrast, is a nonfunctional pseudogene.

Other names

HSPE1 pseudogene 8

Not applicable.