Heat shock transcription factor 2 pseudogene (HSF2 pseudogene)

The "heat shock transcription factor 2 pseudogene" (ENSG00000257350) is a non-functional genomic locus that shares sequence similarity with the protein-coding heat shock transcription factor 2 gene but is classified as a pseudogene due to mutations or deletions that prevent transcription, translation, or protein function. Most pseudogenes, including this one, result from gene duplication or retrotransposition followed by accumulation of disabling mutations. While some pseudogenes may play regulatory roles through RNA transcripts or microRNA decoy functions, there is no evidence this particular pseudogene is a therapeutic target, encodes a functional protein, or is directly implicated in disease.

Other names

HSF2 pseudogene

None applicable; no evidence for drug targeting