Helminth Glucose Transporter (SGTP)

Helminth glucose transporters are membrane proteins located on the tegument or intestinal lining of parasitic worms, facilitating the uptake of glucose from the host. These transporters are essential for the parasite's survival and represent potential targets for anthelmintic drug development. They are also implicated in modulating host metabolism, with some helminth infections showing potential benefits in improving insulin sensitivity and lowering blood glucose in diabetic individuals, though this is still under investigation.

Other names

Schistosome Glucose Transporter ProteinTegumental Glucose TransporterIntestinal D-glucose transporter

Inhibition of glucose uptake leading to parasite starvation