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Hemagglutinin antigen of Influenza B Victoria lineage
- Molecular classification
- Surface glycoprotein, Viral protein, Hemagglutinin
01
Overview
The hemagglutinin (HA) antigen is a major surface glycoprotein of the Influenza B virus, specifically from the Victoria lineage. HA plays a critical role in viral entry by binding to host cell receptors and facilitating membrane fusion. The Victoria lineage is one of two main genetic and antigenic lineages of Influenza B, the other being Yamagata. As a primary target for neutralizing antibodies, antigenic drift in HA necessitates ongoing surveillance and regular updates to vaccine formulations.
- Other names
- Influenza B Victoria lineage HAB/Victoria HA
02
Mechanism of action
Neutralization of viral entry
03
Biological functions
Host cell bindingMembrane fusionAntigen presentationImmune response
04
Disease associations
InfectionInfluenza
05
Safety considerations
Antigenic driftImmune escapeVaccine efficacy
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