Target intelligence / Profile preview

Blood Viscosity

Molecular classification
Physiological Property, Emergent Property
01

Overview

Blood viscosity is a biophysical property describing the thickness and stickiness of blood, reflecting its resistance to flow within the circulatory system. It is a critical determinant of how much friction blood exerts against vessel walls, the workload on the heart during circulation, and how efficiently oxygen is delivered to tissues and organs. Elevated blood viscosity is an independent predictor of cardiovascular events. Blood viscosity is not a direct therapeutic target, but rather an emergent property influenced by multiple factors, including hematocrit, red blood cell deformability and aggregation, and plasma protein concentration.

Other names
Whole Blood ViscosityBlood ThicknessHemorheology
02

Biological functions

Regulation of HemodynamicsCardiovascular FunctionOxygen DeliveryTissue Perfusion
03

Disease associations

Cardiovascular DiseasePolycythemiaAnemiaSickle Cell DiseaseDehydrationThrombosisShock
04

Safety considerations

Impaired CirculationIncreased Cardiovascular RiskReduced Tissue Perfusion
05

Biomarkers

HematocritPlasma Protein ConcentrationRed Blood Cell DeformabilityRed Blood Cell Aggregation

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