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Hemostasis is the physiological process that stops bleeding at sites of vascular injury. Platelets are central to this process, acting as the primary mediators in both the initial and later stages of hemostasis. Their function involves a sequence of tightly regulated steps: adhesion to exposed subendothelial matrix, activation (including shape change and granule release), aggregation to form a platelet plug, and facilitation of coagulation cascade events leading to stable clot formation.
Targeting platelet activation and aggregation pathways to inhibit clot formation.
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