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Target intelligence / Profile preview
Hepatitis B Surface Antigen-Specific Immune Response (Anti-HBs)
- Target
- Anti-HBs
- Molecular classification
- Immune Response
01
Overview
The hepatitis B surface antigen (HBsAg) is a multifunctional glycoprotein and the major antigen of the hepatitis B virus (HBV) envelope. It plays a central role in eliciting both humoral and cellular immune responses during HBV infection. The immune response specifically targeting HBsAg is critical for viral clearance, protection against reinfection, and forms the basis for effective vaccination strategies.
- Other names
- HBsAg Antibody ResponseImmunity to Hepatitis BAnti-HBs antibodies
02
Mechanism of action
Antibody-mediated neutralization of HBV, Cytotoxic T lymphocyte-mediated killing of infected cells, Suppression of viral replication
03
Biological functions
Viral clearanceProtection against reinfectionAdaptive immunityHumoral immunityCellular immunity
04
Disease associations
Hepatitis B infectionViral hepatitisLiver disease
05
Safety considerations
Immune evasion by HBVDevelopment of chronic HBV infectionVaccine non-responsivenessAutoimmune reactions
06
Interacting drugs
Hepatitis B Vaccine
3 more in the full profile.
07
Biomarkers
Anti-HBs antibody titerHBsAg levelHBV DNA levelALT level
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