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Target intelligence / Profile preview
Hepatitis B Virus (HBV)
- Target
- HBV
- Molecular classification
- Virus, DNA virus, Hepadnaviridae
01
Overview
Hepatitis B virus (HBV) is a small, enveloped DNA virus that infects the liver and causes hepatitis B, a disease that can be either acute or chronic. HBV infection is a major global health concern, leading to significant morbidity and mortality due to its association with cirrhosis and hepatocellular carcinoma (liver cancer).
02
Mechanism of action
Inhibition of viral polymerase activity (Entecavir, Tenofovir), Immunomodulation (Interferon alpha)
03
Biological functions
Viral replicationInfectionPathogenesis
04
Disease associations
Hepatitis BLiver cirrhosisHepatocellular carcinoma
05
Safety considerations
Drug resistanceAdverse effects of antiviral medicationsRisk of liver damageReactivation of HBV in immunocompromised patients
06
Interacting drugs
Entecavir
2 more in the full profile.
07
Biomarkers
HBsAgHBeAgHBV DNA viral load
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