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HERC2 pseudogene 1 (HERC2P1)

Target: HERC2P1
Molecular classification: Other (pseudogene, non-coding RNA)

Overview

HERC2 pseudogene 1 (HERC2P1) is a human pseudogene, meaning it is a DNA segment similar to the HERC2 gene but thought to be non-functional or non-protein-coding. Pseudogenes are typically considered "genomic fossils" that arose from gene duplication or retrotransposition events. While HERC2 itself encodes an E3 ubiquitin ligase implicated in DNA repair and genome stability, HERC2P1 is not known to produce a functional protein and is not recognized as a therapeutic target. Some related pseudogenes in the HERC family (like HERC2P2) have been investigated for potential non-coding RNA functions in cancer biology, including biomarker roles, but there is no published evidence for such a role for HERC2P1. The nomenclature "D15F37S2" is an alternative, less frequently used synonym.

Other names: HERC2P1D15F37S2

Biological functions

Other (no direct, protein-mediated function; possible regulatory RNA function via ceRNA effect in cancer subtypes for related pseudogenes)

Disease associations

Other (no confirmed protein function; some pseudogenes in HERC2 family implicated as biomarkers or in cancer prognosis and regulation, especially through non-coding RNA effects; not established for HERC2P1 specifically)

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