Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Herpes Simplex Virus DNA Synthesis (HSV DNA Synthesis)
- Target
- HSV DNA Synthesis
- Molecular classification
- Viral Process
01
Overview
Herpes simplex virus (HSV) DNA synthesis refers to the process by which HSV replicates its double-stranded DNA genome within infected host cells. This is a critical step in the viral life cycle, enabling the production of new virions and propagation of infection. The process involves a cascade of viral proteins, including UL9, ICP8, UL30, UL42, UL5, UL8, and UL52, and relies on a theta-type replication mechanism that transitions to a rolling-circle mode. The unique HSV DNA polymerase is a major target for antiviral drugs.
- Other names
- HSV ReplicationHerpes Simplex Virus Genome ReplicationHSV Genome Duplication
02
Mechanism of action
Inhibition of viral DNA polymerase
03
Biological functions
Viral ReplicationGenome DuplicationViral Propagation
04
Disease associations
Infection
05
Safety considerations
Drug resistanceOff-target effects of antivirals
06
Interacting drugs
Acyclovir
Beyond the preview
Go deeper on Herpes Simplex Virus DNA Synthesis (HSV DNA Synthesis).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Herpes Simplex Virus DNA Synthesis (HSV DNA Synthesis).