Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Herpes Simplex Virus Glycoprotein D (gD)
- Target
- gD
- Molecular classification
- Viral glycoprotein, Envelope protein
01
Overview
Herpes simplex virus glycoprotein D (gD) is an essential envelope protein found in both HSV-1 and HSV-2. It plays a critical role in viral entry into host cells by mediating the initial interaction between the virus and specific cellular receptors on the host cell surface. Upon binding to one of these receptors, gD undergoes conformational changes that trigger downstream interactions with other viral glycoproteins—specifically gB and the gH/gL complex—culminating in fusion of the viral envelope with the host cell membrane and subsequent entry of viral genetic material.
02
Mechanism of action
N/A
03
Biological functions
Virus-host cell entryReceptor bindingMembrane fusion
04
Disease associations
InfectionHerpes simplex virus type 1 infectionHerpes simplex virus type 2 infection
Beyond the preview
Go deeper on Herpes Simplex Virus Glycoprotein D (gD).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Herpes Simplex Virus Glycoprotein D (gD).