Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Herpes simplex virus type 1 (HSV-1)
- Target
- HSV-1
- Molecular classification
- Virus, DNA virus, Herpesviridae, Alphaherpesvirinae
01
Overview
Herpes simplex virus type 1 is a widespread human pathogen responsible primarily for oral herpes but capable of causing diverse clinical syndromes through its ability to establish lifelong latency within sensory neurons followed by periodic reactivation. Its structure includes a dsDNA genome within an enveloped capsid. While incurable at present due to its latent reservoir in nerve tissue, antiviral therapy can manage acute episodes effectively.
02
Mechanism of action
Inhibition of viral DNA polymerase
03
Biological functions
Viral replicationImmune evasionLatencyReactivation
04
Disease associations
InfectionOral herpesGenital herpesOcular infectionsEncephalitisHerpetic whitlow
05
Safety considerations
Drug resistanceReactivation of latent virusLimited efficacy in eradicating latent virus
06
Interacting drugs
Acyclovir
Beyond the preview
Go deeper on Herpes simplex virus type 1 (HSV-1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Herpes simplex virus type 1 (HSV-1).