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Heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2)
- Target
- HNRNPA1L2
- Molecular classification
- RNA-binding protein, hnRNP family, Other
01
Overview
Heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2) is a member of the hnRNP family of RNA-binding proteins. It is primarily involved in the packaging of pre-mRNA into hnRNP particles, facilitating the processing and transport of mRNA from the nucleus to the cytoplasm, and may modulate splice site selection during mRNA maturation[5][7][8][9]. While its homolog hnRNP A1 is well-characterized and associated with various cellular processes such as regulation of gene expression, response to cellular stress, and telomerase activity, the specific role of HNRNPA1L2 is less defined, though it is predicted to share similar functions due to significant homology[5][7][8][9]. Direct clinical or disease associations, validated interacting drugs, or known biomarker or therapeutic roles for HNRNPA1L2 are not currently established in the available literature.
- Other names
- HNRNPA1L2HNRNPA1LhnRNP A1-like 2LOC144983hnRNP core protein A1-like 2heterogeneous nuclear ribonucleoprotein A1-like 2
02
Biological functions
pre-mRNA packagingmRNA splicing via spliceosomeRNA bindingtransport of poly(A) mRNA from nucleus to cytoplasmmodulation of splice site selection
03
Disease associations
Other (no direct implication in major diseases such as cancer, neurodegeneration, or cardiovascular disease reported for HNRNPA1L2 itself)
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