Target intelligence / Profile preview

Heterogeneous nuclear ribonucleoprotein A1 pseudogene 43 (HNRNPA1P43)

Target
HNRNPA1P43
Molecular classification
Pseudogene, Other
01

Overview

Heterogeneous nuclear ribonucleoprotein A1 pseudogene 43 (HNRNPA1P43) is a human pseudogene related by sequence to the HNRNPA1 gene, which encodes a well-known RNA-binding protein involved in RNA splicing, transport, and regulation[1][2][4]. As a pseudogene, HNRNPA1P43 is characterized by its lack of a protein-coding potential due to accumulated mutations and is not believed to be translated into a functional protein[1][5]. While some pseudogenes are transcribed and can influence cellular processes through RNA-mediated mechanisms, no specific functional, therapeutic, or disease-related role has been attributed to HNRNPA1P43 in the scientific literature[1][5]. It is primarily used as a genomic marker for studies on gene family evolution or genomic organization. Key distinction: HNRNPA1P43 should not be confused with HNRNPA1 (without "P43"), which is the functional, protein-coding gene for Heterogeneous nuclear ribonucleoprotein A1[2][4].

Other names
HNRNPA1P43Ensembl: ENSG00000214204NCBI Gene: 400769HGNC: 48772
02

Mechanism of action

None (not a target for any pharmacological agent)

03

Biological functions

May have indirect functions at the RNA level (e.g., regulation of gene expression, ceRNA activity)Does not encode a functional protein productNo specific biological activity or function reported
04

Disease associations

Other (pseudogene)No direct disease association or role documented for HNRNPA1P43 itself

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