Heterogeneous nuclear ribonucleoprotein A1 pseudogene 62 (HNRNPA1P62)

HNRNPA1P62, or Heterogeneous nuclear ribonucleoprotein A1 pseudogene 62, is a pseudogene—meaning it is a non-functional copy of the active HNRNPA1 gene that encodes the hnRNP A1 protein[1]. Pseudogenes are DNA sequences derived from ancestral or active genes but usually accumulate mutations that prevent them from producing a functional protein[7]. While some pseudogenes have regulatory, epigenetic, or non-coding RNA roles in certain biological contexts (e.g., as competitive endogenous RNAs in cancer), there is no specific evidence that HNRNPA1P62 has direct biological or pathological significance. Unlike the parent HNRNPA1 gene/protein, HNRNPA1P62 does not participate in RNA binding, RNA splicing, or regulation of gene expression, nor is it a recognized drug target or biomarker[1][7]. If the intent is to study therapeutic targets in the hnRNP family, the protein-coding gene **HNRNPA1** (heterogeneous nuclear ribonucleoprotein A1) would be the canonical molecule of interest, distinct from this pseudogene.

Other names

hnRNP A1P62HNRNPA1P62

None currently described—for drugs, since it is not a functional protein target.