Target intelligence / Profile preview

Heterogeneous nuclear ribonucleoprotein A1 pseudogene 65 (HNRNPA1P65)

Target
HNRNPA1P65
Molecular classification
Other (processed pseudogene)
01

Overview

Heterogeneous nuclear ribonucleoprotein A1 pseudogene 65 (HNRNPA1P65) is a processed pseudogene and does not code for an active protein product. It is cataloged in genomic resources due to its high sequence similarity to the parental HNRNPA1 gene, but it contains mutations that prevent conventional gene function. Pseudogenes like HNRNPA1P65 may be transcribed at the RNA level, but there is currently no evidence that HNRNPA1P65 acts as a functional regulatory RNA, competitive endogenous RNA, or otherwise contributes to physiological or pathological processes. The functional protein HNRNPA1 is involved in various RNA processing events, but HNRNPA1P65 (the pseudogene) itself lacks established biological function. HNRNPA1P65 itself is a pseudogene and not a canonical drug target, receptor, enzyme, or functional category molecule. Submitting it as a therapeutic target is likely a misunderstanding; the functional molecule of interest in most biomedical contexts is "Heterogeneous nuclear ribonucleoprotein A1" (HNRNPA1), not its pseudogenes. If your interest is in the bona fide protein, you should use "Heterogeneous nuclear ribonucleoprotein A1" as the canonical name.

02

Mechanism of action

Not applicable.

03

Biological functions

None directly established specific to HNRNPA1P65; as a pseudogene it does not encode a functional protein
04

Disease associations

None directly established for HNRNPA1P65. More generally, pseudogene expression is an area of study in cancer biology, but there are no data implicating HNRNPA1P65 specifically as a disease driver or biomarker
05

Biomarkers

None established for this specific pseudogene.

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