Target intelligence / Profile preview

Heterogeneous nuclear ribonucleoprotein K antisense RNA 1 (HNRNPK-AS1)

Target
HNRNPK-AS1
Molecular classification
Long non-coding RNA, Antisense RNA, lncRNA, Other
01

Overview

HNRNPK Antisense RNA 1 (HNRNPK-AS1) is a gene that transcribes a long non-coding RNA classified as an antisense RNA relative to the HNRNPK gene. It belongs to the lncRNA class. Evidence currently links HNRNPK-AS1 primarily to genetic regulation at the RNA level, with potential but not definitively established roles in disease. It is cataloged as associated with conditions such as Au-Kline syndrome, although the mechanistic or causal involvement remains unclear. There is no evidence that it acts as a conventional drug target, nor is it associated with therapeutically actionable mechanisms at present[4].

Other names
HNRNPK antisense RNA 1HNRNPK-AS1
02

Biological functions

Regulation of gene expressionRNA interaction/modulationPossible involvement in cell proliferation and cell cycle regulation (inferred from related antisense RNAs and the function of similar lncRNAs, but no specific functions are curated for HNRNPK-AS1 itself in the sources provided)
03

Disease associations

Potential association with Au-Kline syndromeOther (limited direct disease association evidence; see below)

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