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Target intelligence / Profile preview
HHATL antisense RNA 1 (HHATL-AS1)
- Target
- HHATL-AS1
- Molecular classification
- Long non-coding RNA, Antisense RNA
01
Overview
HHATL antisense RNA 1 (HHATL-AS1) is a long non-coding antisense RNA produced from the HHATL gene locus, likely functioning via complementary base pair interaction with the HHATL mRNA. As with other antisense long non-coding RNAs, it may regulate the expression of its sense transcript (HHATL) through mechanisms that include transcriptional interference, modulation of chromatin marks, or alteration of mRNA stability[1][2][5]. These types of non-coding RNA transcripts are increasingly recognized for their roles in fine-tuning gene expression, chromatin organization, and epigenetic regulation, primarily acting locally (cis) at their site of synthesis[1]. There is currently no published evidence that HHATL-AS1 plays a disease-related role, interacts with drugs, or serves as a recognized clinical biomarker, and it is not considered a canonical therapeutic target.
- Other names
- HHATL antisense RNA 1 (non-protein coding)HHATL-AS1
02
Biological functions
Regulation of gene expressionPotential modulation of local chromatin structurePotential cis or trans transcriptional regulation of neighboring HHATL gene (inferred from general properties of antisense lncRNAs)
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